Peter Philippsen

Functional selection and analysis of yeast centromeric DNA

Mutational analysis of centromere DNA from chromosome VI of Saccharomyces cerevisiae.

Saccharomyces cerevisiae centromeres have a characteristic 120-base-pair region consisting of three distinct centromere DNA sequence elements (CDEI, CDEII, and CDEIII). We have ...

Centromeric DNA from chromosome VI in Saccharomyces cerevisiae strains.

Functional profiling of the Saccharomyces cerevisiae genome

Determining the effect of gene deletion is a fundamental approach to understanding gene function. Conventional genetic screens exhibit biases, and genes contributing to a phenot...

The <i>Ashbya gossypii</i> Genome as a Tool for Mapping the Ancient <i>Saccharomyces cerevisiae</i> Genome

We have sequenced and annotated the genome of the filamentous ascomycete Ashbya gossypii . With a size of only 9.2 megabases, encoding 4718 protein-coding genes, it is the small...

Analysis of chromosomal integration and deletions of yeast plasmids

Plasmid DNAs from six strains of Saccharomyces cerevisiae were compared. Three different plasmids were found, designated Scp 1, Scp 2 and Scp 3, with monomer lengths of 6.19, 6....