Minkyung Baek

Accurate prediction of protein structures and interactions using a three-track neural network

Deep learning takes on protein folding In 1972, Anfinsen won a Nobel prize for demonstrating a connection between a protein’s amino acid sequence and its three-dimensional struc...

Generalized biomolecular modeling and design with RoseTTAFold All-Atom

Deep-learning methods have revolutionized protein structure prediction and design but are presently limited to protein-only systems. We describe RoseTTAFold All-Atom (RFAA), whi...

Accurate prediction of protein–nucleic acid complexes using RoseTTAFoldNA

Generalized Biomolecular Modeling and Design with RoseTTAFold All-Atom

Abstract Although AlphaFold2 (AF2) and RoseTTAFold (RF) have transformed structural biology by enabling high-accuracy protein structure modeling, they are unable to model covale...