Capturing Chromosome Conformation
We describe an approach to detect the frequency of interaction between any two genomic loci. Generation of a matrix of interaction frequencies between sites on the same or diffe...
Publications
5 shownChromosome Conformation Capture Carbon Copy (5C): A massively parallel solution for mapping interactions between genomic elements
Physical interactions between genetic elements located throughout the genome play important roles in gene regulation and can be identified with the Chromosome Conformation Captu...
Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome
Chromosomal Mapping The conformation of the genome in the nucleus and contacts between both proximal and distal loci influence gene expression. In order to map genomic contacts,...
Gene Regulation in the Third Dimension
Analysis of the spatial organization of chromosomes reveals complex three-dimensional networks of chromosomal interactions. These interactions affect gene expression at multiple...
Mapping in Vivo Chromatin Interactions in Yeast Suggests an Extended Chromatin Fiber with Regional Variation in Compaction
The higher order arrangement of nucleosomes and the level of compaction of the chromatin fiber play important roles in the control of gene expression and other genomic activitie...
Frequent Co-Authors
Researcher Info
- h-index
- 5
- Publications
- 5
- Citations
- 14,527
- Institution
- Harvard University
External Links
Identifiers
- ORCID
- 0000-0001-5631-0698
Impact Metrics
h-index
5
h-index: Number of publications with at least h citations each.