Gerard D. Schellenberg

Tau is a candidate gene for chromosome 17 frontotemporal dementia

Abstract Frontotemporal dementia with parkinsonism, chromosome 17 type (FTDP‐17), a recently defined disease entity, is clinically characterized by personality changes sometimes...

A framework for the interpretation of de novo mutation in human disease

Early Alzheimer's disease genetics

The genetics community working on Alzheimer's disease and related dementias has made remarkable progress in the past 20 years. The cumulative efforts by multiple groups have lea...

Genetic Linkage Evidence for a Familial Alzheimer's Disease Locus on Chromosome 14

Linkage analysis was used to search the genome for chromosomal regions harboring familial Alzheimer's disease genes. Markers on chromosome 14 gave highly significant positive lo...