Douglas F. Easton

Publications

3 shown

A Hypermutation Phenotype and Somatic <i>MSH6</i> Mutations in Recurrent Human Malignant Gliomas after Alkylator Chemotherapy

Chris Hunter , Raffaella Smith , Daniel P. Cahill +52 more

Abstract Malignant gliomas have a very poor prognosis. The current standard of care for these cancers consists of extended adjuvant treatment with the alkylating agent temozolom...

2006 Cancer Research 426 citations

The landscape of cancer genes and mutational processes in breast cancer

Philip J. Stephens , Patrick Tarpey , Helen Davies +59 more

All cancers carry somatic mutations in their genomes. A subset, known as driver mutations, confer clonal selective advantage on cancer cells and are causally implicated in oncog...

2012 Nature 1700 citations

Multifactorial Analysis of Differences Between Sporadic Breast Cancers and Cancers Involving BRCA1 and BRCA2 Mutations

Sunil R. Lakhani , J Jacquemier , J P Sloane +38 more

Our study has identified key features of the histologic phenotypes of breast cancers in carriers of mutant BRCA1 and BRCA2 genes. This information may improve the classification...

1998 JNCI Journal of the National Cancer I... 692 citations

Researcher Info

h-index: 3
Publications: 3
Citations: 2,818
Institution: Cancer Research UK

External Links

ORCID Profile Google Scholar

Identifiers

ORCID: 0000-0003-2444-3247

Impact Metrics

h-index 3

h-index: Number of publications with at least h citations each.

Publications

A Hypermutation Phenotype and Somatic <i>MSH6</i> Mutations in Recurrent Human Malignant Gliomas after Alkylator Chemotherapy

The landscape of cancer genes and mutational processes in breast cancer

Multifactorial Analysis of Differences Between Sporadic Breast Cancers and Cancers Involving BRCA1 and BRCA2 Mutations

Frequent Co-Authors

Chris Hunter

Raffaella Smith

Daniel P. Cahill

Philip Stephens

Claire Stevens

Jon W. Teague

Researcher Info

External Links

Identifiers

Impact Metrics