Publications
12 shownGlobal patterns of 16S rRNA diversity at a depth of millions of sequences per sample
The ongoing revolution in high-throughput sequencing continues to democratize the ability of small groups of investigators to map the microbial component of the biosphere. In pa...
UniFrac: a New Phylogenetic Method for Comparing Microbial Communities
ABSTRACT We introduce here a new method for computing differences between microbial communities based on phylogenetic information. This method, UniFrac, measures the phylogeneti...
Evolution of Mammals and Their Gut Microbes
Mammals are metagenomic in that they are composed of not only their own gene complements but also those of all of their associated microbes. To understand the coevolution of the...
Global patterns in bacterial diversity
Microbes are difficult to culture. Consequently, the primary source of information about a fundamental evolutionary topic, life's diversity, is the environmental distribution of...
Fast UniFrac: facilitating high-throughput phylogenetic analyses of microbial communities including analysis of pyrosequencing and PhyloChip data
Abstract Next-generation sequencing techniques, and PhyloChip, have made simultaneous phylogenetic analyses of hundreds of microbial communities possible. Insight into community...
Short pyrosequencing reads suffice for accurate microbial community analysis
Pyrosequencing technology allows us to characterize microbial communities using 16S ribosomal RNA (rRNA) sequences orders of magnitude faster and more cheaply than has previousl...
Evolution of Symbiotic Bacteria in the Distal Human Intestine
The adult human intestine contains trillions of bacteria, representing hundreds of species and thousands of subspecies. Little is known about the selective pressures that have s...
Ribosomal RNA diversity predicts genome diversity in gut bacteria and their relatives
The mammalian gut is an attractive model for exploring the general question of how habitat impacts the evolution of gene content. Therefore, we have characterized the relationsh...
Frequent Co-Authors
Researcher Info
- h-index
- 12
- Publications
- 12
- Citations
- 83,384
- Institution
- University of Colorado Anschutz Medical Campus
External Links
Identifiers
- ORCID
- 0000-0003-4786-7202
Impact Metrics
h-index: Number of publications with at least h citations each.