Adrian G. Sacher

Publications

2 shown

KRAS G12C Inhibition with Sotorasib in Advanced Solid Tumors

David S. Hong , Marwan Fakih , John H. Strickler +31 more

Sotorasib showed encouraging anticancer activity in patients with heavily pretreated advanced solid tumors harboring the KRAS p.G12C mutation. Grade 3 or 4 treatment-rela...

2020 New England Journal of Medicine 1570 citations

Sotorasib for Lung Cancers with KRAS p.G12C Mutation

Ferdinandos Skoulidis , Bob T. Li , Grace K. Dy +23 more

In this phase 2 trial, sotorasib therapy led to a durable clinical benefit without new safety signals in patients with previously treated KRAS p.G12C-mutated NSCLC. (Fund...

2021 New England Journal of Medicine 1567 citations

Frequent Co-Authors

Researcher Info

h-index: 2
Publications: 2
Citations: 3,137
Institution: Princess Margaret Cancer Centre

External Links

ORCID Profile Google Scholar

Identifiers

ORCID: 0000-0001-7865-2701

Impact Metrics

h-index 2

h-index: Number of publications with at least h citations each.

Publications

KRAS <sup>G12C</sup> Inhibition with Sotorasib in Advanced Solid Tumors

Sotorasib for Lung Cancers with <i>KRAS</i> p.G12C Mutation

Frequent Co-Authors

David S. Hong

Marwan Fakih

John H. Strickler

Jayesh Desai

Gregory A. Durm

Geoffrey I. Shapiro

Researcher Info

External Links

Identifiers

Impact Metrics